Raloxifene (Evista) is a selective estrogen receptor modulator used to prevent and treat osteoporosis in postmenopausal women.
Reviewed by:
Dr. Steve Malen, PharmD
Dr. Steven Blikstein, PharmD
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Raloxifene (Evista) is a selective estrogen receptor modulator (SERM) that mimics estrogen's beneficial effects on bone density while blocking estrogen's effects on breast and uterine tissue. It is FDA-approved for the prevention and treatment of osteoporosis in postmenopausal women, and also for reducing the risk of invasive breast cancer in postmenopausal women at high risk. Raloxifene carries a boxed warning for increased risk of venous thromboembolism (blood clots) and should be discontinued before prolonged immobilization, such as long-haul travel or surgery.
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