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Guanfacine: Uses, Dosage, Side Effects, and More

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Guanfacine is prescription medications that act on nerve signals in the brain to lower blood pressure or manage ADHD symptoms. Tenex (immediate-release) is used for hypertension, while Intuniv (extended-release) is approved for treating ADHD in children and adolescents. As central alpha-2 adrenergic agonists, they relax blood vessels, reduce heart rate, and help improve focus and impulse control.

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Controlled Substance Warning

Guanfacine is not controlled substances. They must be taken exactly as prescribed and not stopped abruptly, as sudden discontinuation can cause a sharp increase in blood pressure. Common side effects include drowsiness, dry mouth, dizziness, and constipation.

Drug Facts

Generic Name

Guanfacine

Brand Names

Tenex, Intuniv

Drug Type

Central alpha-2 adrenergic agonist

Dosage Forms

Tablets (immediate-release, extended-release)

Typical Dosage
  • Tenex (hypertension): Start with 0.51 mg at bedtime; may increase gradually up to 2 mg daily.
  • Intuniv (ADHD): Start with 1 mg once daily; increase by 1 mg weekly up to 4 mg daily as tolerated.
  • Take extended-release tablets whole; do not crush or chew.

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Disclaimer

The information provided on this page is for general informational purposes only and is not intended as medical advice. Always consult with a licensed healthcare provider before starting, stopping, or changing any medication regimen. While Invictus strives to provide accurate and up-to-date information, individual health conditions and circumstances vary. The prices, availability, and descriptions of all medications on this page are subject to change.

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