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Amitriptyline: Uses, Dosage, Side Effects, and More
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Amitriptyline Hydrochloride is a prescription antidepressant used to treat major depressive disorder (MDD) and, in some cases, chronic pain, migraine prevention, and sleep disturbances related to depression. As a tricyclic antidepressant (TCA), it boosts certain neurotransmitters in the brain, such as serotonin and norepinephrine. Elavil helps improve mood, relieve anxiety and tension, and promote better sleep.
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Controlled Substance Warning
Amitriptyline is not a controlled substance. It is available by prescription only and should be taken exactly as directed by a healthcare provider. Abruptly stopping the medication may lead to withdrawal symptoms, so tapering is recommended under medical supervision.
Drug Facts
Generic Name
Amitriptyline Hydrochloride
Brand Names
Elavil (discontinued brand), Amitid, Endep (brand equivalents)
Drug Type
Tricyclic antidepressant (TCA)
Dosage Forms
Tablets (oral), intravenous solution (IV infusion)
Typical Dosage
- Depression: 25–50 mg once daily at bedtime; may increase gradually to 100–300 mg per day as needed
- Chronic pain or migraine prevention (off-label): 10–75 mg once daily, typically at bedtime
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Disclaimer
The information provided on this page is for general informational purposes only and is not intended as medical advice. Always consult with a licensed healthcare provider before starting, stopping, or changing any medication regimen. While Invictus strives to provide accurate and up-to-date information, individual health conditions and circumstances vary. The prices, availability, and descriptions of all medications on this page are subject to change.
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