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Bupropion: Uses, Dosage, Side Effects, and More
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Bupropion Hydrochloride is a prescription antidepressant used to treat major depressive disorder (MDD) and seasonal affective disorder (SAD). It works by balancing norepinephrine and dopamine levels in the brain to improve mood, energy, and focus. Often chosen for its lower risk of sexual side effects or weight gain, it may also be prescribed off-label for smoking cessation or attention-related symptoms.
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Controlled Substance Warning
Bupropion Hydrochloride is not a controlled substance. It must be taken exactly as prescribed, as exceeding the dose or stopping suddenly can increase seizure risk. It should not be used by individuals with seizure or eating disorders, or those discontinuing alcohol or sedatives abruptly.
Drug Facts
Generic Name
Bupropion Hydrochloride
Brand Names
Wellbutrin, Wellbutrin SR, Wellbutrin XL
Drug Type
Atypical antidepressant (norepinephrine-dopamine reuptake inhibitor, or NDRI)
Dosage Forms
Tablets (immediate-release, sustained-release, extended-release)
Typical Dosage
- Major depressive disorder (MDD): 150 mg once daily, may increase to 300 mg daily after several days; maximum 450 mg/day depending on formulation.
- Seasonal affective disorder (SAD): 150 mg once daily in the morning, increased to 300 mg daily as directed.
- Doses vary by formulation—follow prescribing instructions carefully. Tablets must be swallowed whole, not crushed or chewed.
- Children (6–11 years): 2 inhalations of 80/4.5 mcg twice daily, if prescribed. Dosage may vary depending on disease severity and prior therapy.
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Disclaimer
The information provided on this page is for general informational purposes only and is not intended as medical advice. Always consult with a licensed healthcare provider before starting, stopping, or changing any medication regimen. While Invictus strives to provide accurate and up-to-date information, individual health conditions and circumstances vary. The prices, availability, and descriptions of all medications on this page are subject to change.
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