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Donepezil: Uses, Dosage, Side Effects, and More

Donepezil Hydrochloride is a prescription cholinesterase inhibitor used to treat symptoms of Alzheimer’s disease and other dementias. It works by increasing acetylcholine levels in the brain to improve memory, awareness, and daily functioning. While not a cure, Aricept can slow cognitive decline and enhance quality of life in patients with mild to severe Alzheimer’s disease.

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Controlled Substance Warning

Donepezil is not a controlled substance. It should be taken exactly as prescribed, usually once daily at bedtime. Mild nausea or diarrhea may occur initially but often lessen over time. Do not stop taking Aricept suddenly without medical guidance, as symptoms may worsen.

Drug Facts

Generic Name

Donepezil Hydrochloride

Brand Names

Aricept

Drug Type

Cholinesterase inhibitor (anti-dementia agent)

Dosage Forms

Tablets, orally disintegrating tablets (ODT)

Typical Dosage
  • Mild to moderate Alzheimer’s disease: Start with 5 mg once daily at bedtime; may increase to 10 mg once daily after 4–6 weeks if tolerated.
  • Moderate to severe Alzheimer’s disease: Doses may be increased to 23 mg once daily after at least 3 months on 10 mg daily.
  • Dosing should be individualized based on clinical response and tolerance.

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Disclaimer

The information provided on this page is for general informational purposes only and is not intended as medical advice. Always consult with a licensed healthcare provider before starting, stopping, or changing any medication regimen. While Invictus strives to provide accurate and up-to-date information, individual health conditions and circumstances vary. The prices, availability, and descriptions of all medications on this page are subject to change.

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