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Duloxetine: Uses, Dosage, Side Effects, and More
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Duloxetine Hydrochloride is a prescription SNRI antidepressant used to treat major depressive disorder (MDD), generalized anxiety disorder (GAD), and chronic pain conditions such as diabetic neuropathy, fibromyalgia, and osteoarthritis-related discomfort. By increasing serotonin and norepinephrine levels it helps regulate mood, energy, and pain perception. Cymbalta addresses both emotional and physical symptoms and is often part of a broader treatment plan.
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Controlled Substance Warning
Duloxetine is not a controlled substance. It should be taken exactly as prescribed and not stopped abruptly to avoid withdrawal symptoms like dizziness or nausea. It may take several weeks to become fully effective, and patients should be monitored for mood or behavioral changes during treatment.
Drug Facts
Generic Name
Duloxetine Hydrochloride
Brand Names
Cymbalta
Drug Type
Serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant
Dosage Forms
Delayed-release capsules (oral)
Typical Dosage
- Major depressive disorder / generalized anxiety disorder: Start with 30 mg once daily for 1 week, then increase to 60 mg once daily as tolerated (maximum 120 mg daily).
- Diabetic nerve pain/fibromyalgia / chronic pain: 60 mg once daily is typical; some patients may start at 30 mg daily.
- Doses should be individualized based on the condition being treated and patient response. Capsules should be swallowed whole, not crushed or chewed.
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Disclaimer
The information provided on this page is for general informational purposes only and is not intended as medical advice. Always consult with a licensed healthcare provider before starting, stopping, or changing any medication regimen. While Invictus strives to provide accurate and up-to-date information, individual health conditions and circumstances vary. The prices, availability, and descriptions of all medications on this page are subject to change.
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