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Fluticasone and Salmeterol: Uses, Dosage, Side Effects, and More

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Fluticasone propionate and Salmeterol is a prescription inhaler used to manage asthma and chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It combines a corticosteroid to reduce airway inflammation and a long-acting beta₂-agonist (LABA) to relax airway muscles, helping to prevent wheezing, coughing, and shortness of breath. It is taken regularly, usually twice daily, for long-term symptom control and is not a rescue inhaler.

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Controlled Substance Warning

Fluticasone/Salmeterol is not a controlled substance. It must be used exactly as prescribed and not for acute asthma attacks—use a fast-acting inhaler instead. Rinse your mouth after each use to prevent oral thrush, and use with caution if you have heart, blood pressure, or seizure conditions.

Drug Facts

Generic Name

Fluticasone Propionate and Salmeterol

Brand Names

Advair Diskus, Advair HFA, AirDuo RespiClick

Drug Type

Combination corticosteroid and long-acting beta₂-agonist (LABA) inhaler

Dosage Forms

Inhalation powder (Diskus), metered-dose inhaler (HFA)

Typical Dosage
  • Asthma (≥12 years): One inhalation of 100/50 mcg, 250/50 mcg, or 500/50 mcg twice daily (approximately 12 hours apart).
  • COPD: One inhalation of 250/50 mcg twice daily.
  • Dose strength is determined by condition severity and patient response.
  • Regular use is necessary for maximum benefit.

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Disclaimer

The information provided on this page is for general informational purposes only and is not intended as medical advice. Always consult with a licensed healthcare provider before starting, stopping, or changing any medication regimen. While Invictus strives to provide accurate and up-to-date information, individual health conditions and circumstances vary. The prices, availability, and descriptions of all medications on this page are subject to change.

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