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The lidocaine 5% patch (Lidoderm) is a topical local anesthetic patch used to relieve pain from postherpetic neuralgia and other localized nerve pain.
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Dr. Steve Malen, PharmD
Dr. Steven Blikstein, PharmD
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The lidocaine 5% patch (Lidoderm) delivers a local anesthetic directly to the skin, blocking sodium channels in peripheral nerves to reduce pain signaling in the applied area. It is FDA-approved for the relief of pain associated with postherpetic neuralgia (pain following shingles) and is also widely used off-label for other localized musculoskeletal and neuropathic pain conditions. The patch should be applied only to intact skin and worn for no more than 12 hours in a 24-hour period to minimize the risk of systemic lidocaine absorption, which can be significant with overuse.
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