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NP Thyroid is a natural desiccated thyroid hormone replacement (containing both T4 and T3) used to treat hypothyroidism.
Reviewed by:
Dr. Steve Malen, PharmD
Dr. Steven Blikstein, PharmD
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NP Thyroid is a natural desiccated thyroid extract derived from porcine thyroid glands, containing both levothyroxine (T4) and liothyronine (T3) in their naturally occurring ratio. It is used as replacement therapy for hypothyroidism in patients whose thyroid gland does not produce enough hormone. Some patients and prescribers prefer desiccated thyroid over synthetic levothyroxine alone because it provides both T3 and T4, though clinical evidence of superiority is limited. As with other thyroid replacement products, dosing is individualized and guided by TSH and clinical symptoms, with caution in elderly patients and those with cardiovascular disease.
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Levothyroxine is a prescription thyroid hormone used to treat hypothyroidism, a condition where the thyroid gland does not produce enough hormone. It works by replacing or supplementing thyroxine (T4), helping regulate metabolism, energy levels, and overall body functions. Synthroid is typically taken once daily, usually on an empty stomach in the morning.

Liothyronine (Cytomel) is a synthetic form of triiodothyronine (T3) thyroid hormone used to treat hypothyroidism.