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Meclizine (Antivert, Bonine) is an antihistamine used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness or vertigo.
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Dr. Steve Malen, PharmD
Dr. Steven Blikstein, PharmD
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Meclizine (Antivert, Bonine) is a first-generation antihistamine that suppresses the vestibular stimulation and nausea signals involved in motion sickness and vertigo, likely through its anticholinergic and central antihistaminic effects. It is used both to prevent motion sickness and to manage vertigo associated with vestibular disorders such as Meniere's disease. Common side effects include drowsiness and dry mouth, and patients should exercise caution when driving or operating machinery until they know how the medication affects them.
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