Guanfacine
High Blood Pressure / ADHD
Guanfacine is a prescription medication that contains guanfacine, a central alpha-2 adrenergic agonist that reduces sympathetic nerve signals in the brain. Depending on the formulation, it is primarily used to treat hypertension by lowering heart rate and relaxing blood vessels, and is also approved for the treatment of ADHD in children and adolescents, helping improve attention, impulse control, and emotional regulation. Guanfacine should not be stopped abruptly, as sudden discontinuation can cause rebound hypertension with symptoms such as rapid heart rate, anxiety, and tremors. Common side effects include drowsiness, dry mouth, dizziness, and constipation.