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Digoxin is a prescription cardiac glycoside used to treat heart failure and atrial fibrillation by helping the heart beat more strongly and regularly. It increases the force of heart contractions while slowing the heart rate, improving circulation, and symptom control. Due to its narrow therapeutic range, regular blood tests are required to ensure safe and effective dosing. Digoxin should be taken exactly as prescribed, at the same time each day, and never adjusted without medical guidance. Overdose or toxicity can cause nausea, dizziness, vision changes, confusion, or irregular heartbeat.

Diltiazem Hydrochloride is a prescription medication used to treat high blood pressure, chest pain (angina), and certain heart rhythm disorders, such as atrial fibrillation or flutter. It relaxes the heart and blood vessel muscles, improving blood flow and lowering blood pressure. Available in immediate- and extended-release forms, Cardizem may be prescribed alone or with other cardiovascular medications.