Norgestimate and Ethinyl Estradiol is a prescription monophasic combination oral contraceptive used to prevent pregnancy. It contains a progestin and an estrogen that prevent ovulation, thicken cervical mucus, and alter the uterine lining to block fertilization or implantation. Sprintec may also help regulate menstrual cycles, reduce cramps, lighten periods, and improve acne in women seeking hormonal birth control.