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Norethindrone Acetate and Ethinyl Estradiol: Uses, Dosage, Side Effects, and More

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Norethindrone Acetate and Ethinyl Estradiol is a prescription combination oral contraceptive used to prevent pregnancy. Containing a progestin and an estrogen, it prevents ovulation, thickens cervical mucus, and alters the uterine lining to stop fertilization and implantation. Loestrin may also help regulate menstrual cycles, reduce cramps, lighten periods, and manage acne or PMS symptoms. Some formulations include iron-containing placebo tablets for consistent daily dosing.

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Controlled Substance Warning

Norethindrone Acetate and Ethinyl Estradiol is not a controlled substance. It must be taken exactly as prescribed, at the same time each day, for maximum effectiveness. Women over 35 who smoke should not use Loestrin due to increased risks of blood clots, stroke, or heart attack. Backup contraception may be needed if doses are missed or vomiting occurs.

Drug Facts

Generic Name

Norethindrone Acetate and Ethinyl Estradiol

Brand Names

Loestrin, Loestrin Fe, Microgestin, Blisovi, Junel

Drug Type

Combined oral contraceptive (estrogen/progestin)

Dosage Forms

Tablets (oral)

Typical Dosage
  • One tablet taken by mouth once daily, at the same time each day.
  • Most 28-day packs contain 21 active tablets (with hormones) and 7 inactive or iron-containing tablets.
  • Start a new pack immediately after finishing the previous one, even if menstruation hasn’t ended.
  • If one active pill is missed, take it as soon as remembered; if two or more are missed, refer to package directions or contact a healthcare provider.

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Disclaimer

The information provided on this page is for general informational purposes only and is not intended as medical advice. Always consult with a licensed healthcare provider before starting, stopping, or changing any medication regimen. While Invictus strives to provide accurate and up-to-date information, individual health conditions and circumstances vary. The prices, availability, and descriptions of all medications on this page are subject to change.

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